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Representative Pooled Matrix as Negative Control is Critical in ADA Assay

The pooled matrix is vital in immunogenicity assays, serving as both negative control and sample preparation matrix, influencing the Screening Cut Point (SCP). Selecting a representative pooled matrix matching individual lots is crucial to avoid abnormal SCP and inaccurate results, necessitating caution during method development.

Representative Pooled Matrix as Negative Control is Critical in ADA Assay\

Amador Case study_Representative Pooled Matrix as Negative Control is Critical in ADA Assay-3

 

 

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